Last update
3/21/2026
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
USERS' SCORE
Good
Based on 4 Reviews
8.2
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin K2(as Menaquinone-7) (MK-7 ) (MenaQ7®)
100 mcg
**
Top Medical Research Studies
8
Vitamin K-dependent GAS6 enhances remyelination
We investigated the role of GAS6 in promoting remyelination, particularly in relation to vitamin K's effect on a type of receptor.
Our findings highlight that GAS6 needs to be modified through vitamin K for proper function.
When introduced to wild-type mice, this treatment significantly increased the number of myelinated axons compared to a control group.
However, in mice lacking the specific Tyro3 receptor, no significant improvement was noted. This indicates that Tyro3 is crucial for the effectiveness of GAS6 in aiding recovery for conditions like multiple sclerosis.
Our findings highlight that GAS6 needs to be modified through vitamin K for proper function.
When introduced to wild-type mice, this treatment significantly increased the number of myelinated axons compared to a control group.
However, in mice lacking the specific Tyro3 receptor, no significant improvement was noted. This indicates that Tyro3 is crucial for the effectiveness of GAS6 in aiding recovery for conditions like multiple sclerosis.
Read More
9
We explored the effect of vitamin K3 on fibrosis in lupus nephritis (LN), a serious complication of systemic lupus erythematosus. The study analyzed kidney biopsy samples and lupus-prone mice, looking particularly at the SIAH2-LATS2 pathway.
Our findings revealed that vitamin K3 can effectively protect against renal fibrotic damage by inhibiting the degradation of LATS2, a protein crucial for controlling fibrosis progression. This suggests a potential new treatment avenue for patients suffering from LN.
Our findings revealed that vitamin K3 can effectively protect against renal fibrotic damage by inhibiting the degradation of LATS2, a protein crucial for controlling fibrosis progression. This suggests a potential new treatment avenue for patients suffering from LN.
Read More
5
We explored the effectiveness of apixaban compared to vitamin K antagonists (VKAs) in preventing thromboembolic events in patients with antiphospholipid syndrome (APS).
In a study involving 152 patients, we tracked complications over a median of 53 months.
The results showed that thromboembolic events were similar between those on apixaban and VKAs, indicating no significant advantage for vitamin K treatment in this context.
Both treatments posed comparable risks for bleeding, suggesting apixaban might be a viable option for some APS patients.
In a study involving 152 patients, we tracked complications over a median of 53 months.
The results showed that thromboembolic events were similar between those on apixaban and VKAs, indicating no significant advantage for vitamin K treatment in this context.
Both treatments posed comparable risks for bleeding, suggesting apixaban might be a viable option for some APS patients.
Read More
Most Useful Reviews
7.5
Reduced hair loss
3 people found this helpful
I began taking K2 (MK-7) to ensure proper calcium absorption with Vitamin D, as my doctor advised to avoid thrombosis. After starting K2 due to hair loss while on Vitamin D alone, my condition has improved significantly now. I take 200 mcg daily.
Read More
7.5
Better absorption
1 people found this helpful
My family and I take Vitamin K-2 with D-3 as directed by our doctor. K2 ensures proper calcium distribution in the body, aiding bone health. The capsule is small and easy to take. We were also pleased with the quick delivery.
Read More
7.5
Prevention of calcification
1 people found this helpful
I take calcium and Vitamin D but added K2 to prevent calcification. K2 assists in calcium and Vitamin D reaching the bones. The multivitamin I had was insufficient, so I’ll repurchase this product.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
- All Researches
9
We explored the effect of vitamin K3 on fibrosis in lupus nephritis (LN), a serious complication of systemic lupus erythematosus. The study analyzed kidney biopsy samples and lupus-prone mice, looking particularly at the SIAH2-LATS2 pathway.
Our findings revealed that vitamin K3 can effectively protect against renal fibrotic damage by inhibiting the degradation of LATS2, a protein crucial for controlling fibrosis progression. This suggests a potential new treatment avenue for patients suffering from LN.
Our findings revealed that vitamin K3 can effectively protect against renal fibrotic damage by inhibiting the degradation of LATS2, a protein crucial for controlling fibrosis progression. This suggests a potential new treatment avenue for patients suffering from LN.
Read More
8
Vitamin K-dependent GAS6 enhances remyelination
We investigated the role of GAS6 in promoting remyelination, particularly in relation to vitamin K's effect on a type of receptor.
Our findings highlight that GAS6 needs to be modified through vitamin K for proper function.
When introduced to wild-type mice, this treatment significantly increased the number of myelinated axons compared to a control group.
However, in mice lacking the specific Tyro3 receptor, no significant improvement was noted. This indicates that Tyro3 is crucial for the effectiveness of GAS6 in aiding recovery for conditions like multiple sclerosis.
Our findings highlight that GAS6 needs to be modified through vitamin K for proper function.
When introduced to wild-type mice, this treatment significantly increased the number of myelinated axons compared to a control group.
However, in mice lacking the specific Tyro3 receptor, no significant improvement was noted. This indicates that Tyro3 is crucial for the effectiveness of GAS6 in aiding recovery for conditions like multiple sclerosis.
Read More
5
We explored the effectiveness of apixaban compared to vitamin K antagonists (VKAs) in preventing thromboembolic events in patients with antiphospholipid syndrome (APS).
In a study involving 152 patients, we tracked complications over a median of 53 months.
The results showed that thromboembolic events were similar between those on apixaban and VKAs, indicating no significant advantage for vitamin K treatment in this context.
Both treatments posed comparable risks for bleeding, suggesting apixaban might be a viable option for some APS patients.
In a study involving 152 patients, we tracked complications over a median of 53 months.
The results showed that thromboembolic events were similar between those on apixaban and VKAs, indicating no significant advantage for vitamin K treatment in this context.
Both treatments posed comparable risks for bleeding, suggesting apixaban might be a viable option for some APS patients.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Reduced hair loss
3 people found this helpful
I began taking K2 (MK-7) to ensure proper calcium absorption with Vitamin D, as my doctor advised to avoid thrombosis. After starting K2 due to hair loss while on Vitamin D alone, my condition has improved significantly now. I take 200 mcg daily.
Read More
7.5
Better absorption
1 people found this helpful
My family and I take Vitamin K-2 with D-3 as directed by our doctor. K2 ensures proper calcium distribution in the body, aiding bone health. The capsule is small and easy to take. We were also pleased with the quick delivery.
Read More
7.5
Prevention of calcification
1 people found this helpful
I take calcium and Vitamin D but added K2 to prevent calcification. K2 assists in calcium and Vitamin D reaching the bones. The multivitamin I had was insufficient, so I’ll repurchase this product.
Read More
7.5
Improved control
6 people found this helpful
My first order was well-packaged. Alongside Vitamin D3, Zinc, and Omega 3, this product has improved my lupus remarkably in just a few months, with lab results now satisfactory. I’m very satisfied with my purchase.
Read More
Frequently Asked Questions
7.5
Improved control
6 people found this helpful
My first order was well-packaged. Alongside Vitamin D3, Zinc, and Omega 3, this product has improved my lupus remarkably in just a few months, with lab results now satisfactory. I’m very satisfied with my purchase.
7.5
Better absorption
1 people found this helpful
My family and I take Vitamin K-2 with D-3 as directed by our doctor. K2 ensures proper calcium distribution in the body, aiding bone health. The capsule is small and easy to take. We were also pleased with the quick delivery.
7.5
Reduced hair loss
3 people found this helpful
I began taking K2 (MK-7) to ensure proper calcium absorption with Vitamin D, as my doctor advised to avoid thrombosis. After starting K2 due to hair loss while on Vitamin D alone, my condition has improved significantly now. I take 200 mcg daily.
9
We explored the effect of vitamin K3 on fibrosis in lupus nephritis (LN), a serious complication of systemic lupus erythematosus. The study analyzed kidney biopsy samples and lupus-prone mice, looking particularly at the SIAH2-LATS2 pathway.
Our findings revealed that vitamin K3 can effectively protect against renal fibrotic damage by inhibiting the degradation of LATS2, a protein crucial for controlling fibrosis progression. This suggests a potential new treatment avenue for patients suffering from LN.
Our findings revealed that vitamin K3 can effectively protect against renal fibrotic damage by inhibiting the degradation of LATS2, a protein crucial for controlling fibrosis progression. This suggests a potential new treatment avenue for patients suffering from LN.
8
Vitamin K-dependent GAS6 enhances remyelination
We investigated the role of GAS6 in promoting remyelination, particularly in relation to vitamin K's effect on a type of receptor.
Our findings highlight that GAS6 needs to be modified through vitamin K for proper function.
When introduced to wild-type mice, this treatment significantly increased the number of myelinated axons compared to a control group.
However, in mice lacking the specific Tyro3 receptor, no significant improvement was noted. This indicates that Tyro3 is crucial for the effectiveness of GAS6 in aiding recovery for conditions like multiple sclerosis.
Our findings highlight that GAS6 needs to be modified through vitamin K for proper function.
When introduced to wild-type mice, this treatment significantly increased the number of myelinated axons compared to a control group.
However, in mice lacking the specific Tyro3 receptor, no significant improvement was noted. This indicates that Tyro3 is crucial for the effectiveness of GAS6 in aiding recovery for conditions like multiple sclerosis.
References
- Sikorska M, Chmiel J, Papuga-Szela E, Broniatowska E, Undas A. Apixaban Versus Vitamin K Antagonists in Patients With Antiphospholipid Syndrome: A Cohort Study. J Cardiovasc Pharmacol. 2024;84:36. 10.1097/FJC.0000000000001578
- Asadian N, Aprico A, Chen M, Yuen D, Johnston APR, et al. The therapeutic effect of GAS6 in remyelination is dependent upon Tyro3. Glia. 2024;72:1392. 10.1002/glia.24534
- Cheng C, Yang H, Yang C, Xie J, Wang J, et al. LATS2 degradation promoted fibrosis damage and rescued by vitamin K3 in lupus nephritis. Arthritis Res Ther. 2024;26:64. 10.1186/s13075-024-03292-y
Data last updated:
